Whole Genome Sequencing of Mycobacterium tuberculosis Clinical Isolates From India Reveals Genetic Heterogeneity and Region-Specific Variations That Might Affect Drug Susceptibility

Whole Genome Sequencing of Mycobacterium tuberculosis Clinical Isolates From India Reveals Genetic Heterogeneity and Region-Specific Variations That Might Affect Drug Susceptibility

Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been constructive in understanding its evolution, genetic diversity and the mechanisms involved in drug resistance. A large number of sequencing efforts from across the globe have revealed genetic diversity among clinical isolates and t...

Full description

Bibliographic Details
Main Authors: Jayshree Advani, Renu Verma, Oishi Chatterjee, Praveen Kumar Pachouri, Prashant Upadhyay, Rajesh Singh, Jitendra Yadav, Farah Naaz, Raju Ravikumar, Shashidhar Buggi, Mrutyunjay Suar, Umesh D. Gupta, Akhilesh Pandey, Devendra S. Chauhan, Srikanth Prasad Tripathy, Harsha Gowda, T. S. Keshava Prasad
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
fluoroquinolones
metagenomics
molecular genotyping
mycobacterial genetic heterogeneity
next generation sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00309/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00309/full

Similar Items