Use of dual-transfection for programmed death cell protein 1 disruption mediated by CRISPR-Cas9 in human peripheral blood mononuclear cells

Objective(s): Checkpoint blocking is considered a revolutionary method in cancer treatment. This method eliminates cancer cells by maintaining the sensitivity of immune cells. Today, cell therapy through checkpoint blocking is known as the most efficient method of cancer treatment. The programmed ce...

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Bibliographic Details
Main Authors: Seyed Ali Alambeladi, Seyed Ebrahim Hosseini, Mojtaba Jafarinia, Mehdi Dianatpour
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
1
Online Access:https://ijbms.mums.ac.ir/article_16961_ce5c071b0fa128c6821ae69f5210dfe9.pdf