Voltage-sensing phosphatase modulation by a C2 domain

The voltage-sensing phosphatase (VSP) is the first example of an enzyme controlled by changes in membrane potential. VSP has four distinct regions: the transmembrane voltage-sensing domain (VSD), the inter-domain linker, the cytosolic catalytic domain and the C2 domain. The VSD transmits the changes...

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Bibliographic Details
Main Authors: Paul M. Castle, Kevin D. Zolman, Susy C. Kohout
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Pharmacology
Subjects:
PIP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00063/full