Detection of Cerebrovascular Loss in the Normal Aging C57BL/6 Mouse Brain Using in vivo Contrast-Enhanced Magnetic Resonance Angiography

Microvascular rarefaction, or the decrease in vascular density, has been described in the cerebrovasculature of aging humans, rats, and, more recently, mice in the presence and absence of age-dependent diseases. Given the wide use of mice in modeling age-dependent human diseases of the cerebrovascul...

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Bibliographic Details
Main Authors: Lindsay K. Hill, Dung Minh Hoang, Luis A. Chiriboga, Thomas Wisniewski, Martin J. Sadowski, Youssef Z. Wadghiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
MRI
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.585218/full