Extra- and Intra-Cellular Mechanisms of Hepatic Stellate Cell Activation

Hepatic fibrosis is characterized by the pathological accumulation of extracellular matrix (ECM) in the liver resulting from the persistent liver injury and wound-healing reaction induced by various insults. Although hepatic fibrosis is considered reversible after eliminating the cause of injury, ch...

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Bibliographic Details
Main Authors: Yufei Yan, Jiefei Zeng, Linhao Xing, Changyong Li
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/8/1014