Sensitive detection and monitoring of senescence-associated secretory phenotype by SASP-RAP assay.

Senescence-associated secretory phenotype (SASP) is characterized by abundant secretion of various proteins in senescent cells and implicated in tumor progression and inflammatory responses. However, the profile of secreted proteins in SASP is different from cell type to cell type, and currently, un...

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Bibliographic Details
Main Authors: Liubao Gu, Masanori Kitamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3525586?pdf=render