Genetic investigation of childhood vascular tumor biology reveals pathways for therapeutic intervention [version 1; peer review: 2 approved]

Vascular tumors are neoplasms of endothelial cells, a significant number of which present in childhood. Recent studies have examined the mutational landscape of many subtypes of vascular tumors, identifying mutations primarily within the Ras–mitogen-activated protein kinase (MAPK) pathway and provid...

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Bibliographic Details
Main Authors: Shayan Cheraghlou, Young Lim, Keith Choate
Format: Article
Language:English
Published: F1000 Research Ltd 2019-04-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-590/v1