Bacterial Flora Play Important Roles in Acute Dextran Sulphate Sodium-Induced Colitis But Are Not Involved in Gal-3 Dependent Modulation of Colon Inflammation
An altered immune response to normal gut microflora is important for the pathogenesis of ulcerative colitis (UC). Galectin- 3 (Gal-3) is an endogenous lectin that plays an important pro-inflammatory role in the induction phase of acute colitis by promoting activation of the NLRP3 infl ammasome and p...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2017-10-01
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Series: | Serbian Journal of Experimental and Clinical Research |
Subjects: | |
Online Access: | https://doi.org/10.1515/sjecr-2017-0022 |