Detection of Viral −RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues

Detection of Viral −RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues

The current methods to study the distribution and dynamics of viral RNA molecules inside infected cells are not ideal, as electron microscopy and immunohistochemistry can only detect mature virions, and quantitative real-time PCR does not reveal localized distribution of RNAs. We demonstrated here t...

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Bibliographic Details
Main Authors: Sami Salmikangas, Jutta E. Laiho, Kerttu Kalander, Mira Laajala, Anni Honkimaa, Iryna Shanina, Sami Oikarinen, Marc S. Horwitz, Heikki Hyöty, Varpu Marjomäki
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Microorganisms
Subjects:
antiviral drugs
branched DNA
enterovirus
in situ hybridization
negative RNA
positive RNA
Online Access:https://www.mdpi.com/2076-2607/8/12/1928

Internet

https://www.mdpi.com/2076-2607/8/12/1928

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