Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells

Mammalian cells have two fundamentally different states, proliferative and quiescent, but our understanding of how and why cells switch between these states is limited. We previously showed that actively proliferating populations contain a subpopulation that enters quiescence (G0) in an apparently s...

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Bibliographic Details
Main Authors: Mansi Arora, Justin Moser, Harsha Phadke, Ashik Akbar Basha, Sabrina L. Spencer
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cell Reports
Subjects:
G0
p21
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717305661