KRAS mutations in primary colorectal cancer tumors and related metastases: a potential role in prediction of lung metastasis.

KRAS mutations in primary colorectal cancer tumors and related metastases: a potential role in prediction of lung metastasis.

BACKGROUND:KRAS mutations in colorectal cancer primary tumors predict resistance to anti-Epidermal Growth Factor Receptor (EGFR) monoclonal antibody therapy in patients with metastatic colorectal cancer, and thus represent a true indicator of EGFR pathway activation status. METHODOLOGY/PRINCIPAL FIN...

Full description

Bibliographic Details
Main Authors: Paloma Cejas, Miriam López-Gómez, Cristina Aguayo, Rosario Madero, Javier de Castro Carpeño, Cristóbal Belda-Iniesta, Jorge Barriuso, Víctor Moreno García, Javier Larrauri, Rocío López, Enrique Casado, Manuel Gonzalez-Barón, Jaime Feliu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2792724?pdf=render

Internet

http://europepmc.org/articles/PMC2792724?pdf=render

Similar Items