The Contribution of Astrocyte and Neuronal Panx1 to Seizures Is Model and Brain Region Dependent
Pannexin1 (Panx1) is an ATP release channel expressed in neurons and astrocytes that plays important roles in CNS physiology and pathology. Evidence for the involvement of Panx1 in seizures includes the reduction of epileptiform activity and ictal discharges following Panx1 channel blockade or delet...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2021-04-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1177/17590914211007273 |