Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells

Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells

<p>Abstract</p> <p>Background</p> <p>The survival of glioma patients with the current treatments is poor. Early clinical trails with replicating adenoviruses demonstrated the feasibility and safety of the use of adenoviruses as oncolytic agents. Antitumor efficacy has b...

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Bibliographic Details
Main Authors: Lamfers Martine L, Uil Taco G, de Vrij Jeroen, van den Hengel Sanne K, Sillevis Smitt Peter AE, Hoeben Rob C
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Virology Journal
Subjects:
glioma
gene therapy
adenovirus
i-leader
oncolytic virus
Online Access:http://www.virologyj.com/content/8/1/162

Internet

http://www.virologyj.com/content/8/1/162

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