Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression

Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression

Clear cell ovarian carcinoma (CCOC) represents a distinct histologic subtype of ovarian cancer associated with significantly worse prognosis across all stages and no effective therapeutic options. Here, we report a rare but clinically important cohort of CCOCs with microsatellite instability (MSI) (...

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Bibliographic Details
Main Authors: Brooke E. Howitt, Kyle C. Strickland, Lynette M. Sholl, Scott Rodig, Lauren L. Ritterhouse, Dipanjan Chowdhury, Alan D. D'Andrea, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:OncoImmunology
Subjects:
clear cell ovarian cancer
immunotherapy
microsatellite instability
pd-1
pd-l1
tumor-infiltrating lymphocytes
Online Access:http://dx.doi.org/10.1080/2162402X.2016.1277308

Internet

http://dx.doi.org/10.1080/2162402X.2016.1277308

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