A Biosimilarity Study Between QX001S and Ustekinumab in Healthy Chinese Male Subjects

A Biosimilarity Study Between QX001S and Ustekinumab in Healthy Chinese Male Subjects

Objective: To evaluate the tolerance, variability, and pharmacokinetics (PK) of QX001S, a biosimilar for ustekinumab, in healthy Chinese men.Methods: One hundred and seventy-eight healthy men were recruited in this randomized, double-blind, single-dose, two-arm, parallel study, and received 45 mg of...

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Bibliographic Details
Main Authors: Lei Gao, Qingmei Li, Hong Zhang, Min Wu, Min Fang, Lizhi Yang, Xiaojiao Li, Jingrui Liu, Cuiyun Li, Hong Chen, Xiaoxue Zhu, Yanhua Ding, Mingwei Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
ustekinumab
biosimilar
immunogenicity
pharmacokinetics
inter-subject variability
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.675358/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.675358/full

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