Impaired clearance of apoptotic cells in chronic inflammatory diseases: therapeutic implications

In healthy individuals billions of cells die by apoptosis every day. Removal of the dead cells by phagocytosis (a process called efferocytosis) must be efficient to prevent secondary necrosis and the consequent release of proinflammatory cell contents that damages the tissue environment and provokes...

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Bibliographic Details
Main Authors: Zsuzsa eSzondy, Éva eGarabuczi, Gergely eJoós, Gregory J. Tsay, Zsolt eSarang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00354/full