Amorphous silica nanoparticles induce tumorigenesis via regulating ATP5H/SOD1-related oxidative stress, oxidative phosphorylation and EIF4G2/PABPC1-associated translational initiation

Background Recent studies indicate amorphous silica nanoparticles (SiNPs), one of the widely applied nanomaterials, have potential toxicity in humans and induces cell malignant transformation. However, its carcinogenic mechanisms remain poorly understood. This study’s purpose was to investigate the...

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Bibliographic Details
Main Authors: Dongli Xie, Yang Zhou, Xiaogang Luo
Format: Article
Language:English
Published: PeerJ Inc. 2019-03-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/6455.pdf