Heterogeneity of Stemlike Circulating Tumor Cells in Invasive Breast Cancer

Heterogeneity of Stemlike Circulating Tumor Cells in Invasive Breast Cancer

The presence of stem and epithelial–mesenchymal-transition (EMT) features in circulating tumor cells (CTCs) determines their invasiveness, adaptability to the microenvironment, and resistance to proapoptotic signals and chemotherapy. It also allows them to fulfil the role of metastatic “seeds”. We e...

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Bibliographic Details
Main Authors: Olga E. Savelieva, Liubov A. Tashireva, Evgeniya V. Kaigorodova, Angelina V. Buzenkova, Rustam Kh. Mukhamedzhanov, Evgeniya S. Grigoryeva, Marina V. Zavyalova, Natalia A. Tarabanovskaya, Nadezhda V. Cherdyntseva, Vladimir M. Perelmuter
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
circulating tumor cells
stemness
EMT
heterogeneity
breast cancer.
Online Access:https://www.mdpi.com/1422-0067/21/8/2780

Internet

https://www.mdpi.com/1422-0067/21/8/2780

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