Fusion genes in gynecologic tumors: the occurrence, molecular mechanism and prospect for therapy

Abstract Gene fusions are thought to be driver mutations in multiple cancers and are an important factor for poor patient prognosis. Most of them appear in specific cancers, thus satisfactory strategies can be developed for the precise treatment of these types of cancer. Currently, there are few tar...

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Bibliographic Details
Main Authors: Bingfeng Lu, Ruqi Jiang, Bumin Xie, Wu Wu, Yang Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04065-0