The role of pparγ and autophagy in ros production, lipid droplets biogenesis and its involvement with colorectal cancer cells modulation

The role of pparγ and autophagy in ros production, lipid droplets biogenesis and its involvement with colorectal cancer cells modulation

Abstract Background In cancer cells, autophagy can act as both tumor suppressor, when autophagic event eliminates cellular contends which exceeds the cellular capacity of regenerate promoting cell death, and as a pro-survival agent removing defective organelles and proteins and helping well-establis...

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Bibliographic Details
Main Authors: José Antonio Fagundes Assumpção, Kelly Grace Magalhães, José Raimundo Corrêa
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Cancer Cell International
Subjects:
Colorectal cancer
Autophagy
PPAR
ROS
Lipid bodies
Cancer stem cells
Online Access:http://link.springer.com/article/10.1186/s12935-017-0451-5

Internet

http://link.springer.com/article/10.1186/s12935-017-0451-5

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