Generation of Adducts of 4-Hydroxy-2-nonenal with Heat Shock 60 kDa Protein 1 in Human Promyelocytic HL-60 and Monocytic THP-1 Cell Lines

Generation of Adducts of 4-Hydroxy-2-nonenal with Heat Shock 60 kDa Protein 1 in Human Promyelocytic HL-60 and Monocytic THP-1 Cell Lines

Heat shock 60 kDa protein 1 (HSP60) is a chaperone and stress response protein responsible for protein folding and delivery of endogenous peptides to antigen-presenting cells and also a target of autoimmunity implicated in the pathogenesis of atherosclerosis. By two-dimensional electrophoresis and m...

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Bibliographic Details
Main Authors: Alessia Arcaro, Martina Daga, Giovanni Paolo Cetrangolo, Eric Stefano Ciamporcero, Alessio Lepore, Stefania Pizzimenti, Claudia Petrella, Maria Graf, Koji Uchida, Gianfranco Mamone, Pasquale Ferranti, Paul R. J. Ames, Giuseppe Palumbo, Giuseppina Barrera, Fabrizio Gentile
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/296146

Internet

http://dx.doi.org/10.1155/2015/296146

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