CRISPR Cpf1 proteins: structure, function and implications for genome editing

CRISPR Cpf1 proteins: structure, function and implications for genome editing

Abstract CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive immune system, allows biologists to edit genomic DNA in a precise and specific way. CRISPR-Cas systems are classified into two main classes and six types. Cpf1 is a putative type V (class II) CRISPR effector, wh...

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Bibliographic Details
Main Authors: Fatemeh Safari, Khadijeh Zare, Manica Negahdaripour, Mazyar Barekati-Mowahed, Younes Ghasemi
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cell & Bioscience
Subjects:
CRISPR/Cas9
CRISPR/Cpf1
Transcription
Epigenetic
Gene editing
Base editing
Online Access:http://link.springer.com/article/10.1186/s13578-019-0298-7

Internet

http://link.springer.com/article/10.1186/s13578-019-0298-7

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