ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy

<p>Abstract</p> <p>Background</p> <p>Autophagy is characterized by the sequestration of cytoplasm and organelles into multimembrane vesicles and subsequent degradation by the cell's lysosomal system. It is linked to many physiological functions in human cells inclu...

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Bibliographic Details
Main Authors: Johnson Kimberly N, Sinha Seema, Barton Christopher E, Marshall Clayton B, Mays Deborah J, Rosenbluth Jennifer M, Eby Kathryn G, Tang Luojia, Pietenpol Jennifer A
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/95