let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

Summary: Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics. This necessity for retina regeneration is often compromised in mammals. We explored the significance of developmentally inevitable Sonic hedgehog signaling and fou...

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Bibliographic Details
Main Authors: Simran Kaur, Shivangi Gupta, Mansi Chaudhary, Mohammad Anwar Khursheed, Soumitra Mitra, Akshai Janardhana Kurup, Rajesh Ramachandran
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471830531X

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http://www.sciencedirect.com/science/article/pii/S221112471830531X

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