Annatto-Derived Tocotrienol Promotes Mineralization of MC3T3-E1 Cells by Enhancing BMP-2 Protein Expression via Inhibiting RhoA Activation and HMG-CoA Reductase Gene Expression

Wan Nuraini Wan Hasan,1 Kok-Yong Chin,1 Norzana Abd Ghafar,2 Ima Nirwana Soelaiman1 1Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, UKM Medical Centre (UKMMC), Kuala Lumpur 56000, Malaysia; 2Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia,...

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Bibliographic Details
Main Authors: Wan Hasan WN, Chin KY, Abd Ghafar N, Soelaiman IN
Format: Article
Language:English
Published: Dove Medical Press 2020-03-01
Series:Drug Design, Development and Therapy
Subjects:
Online Access:https://www.dovepress.com/annatto-derived-tocotrienol-promotes-mineralization-of-mc3t3-e1-cells--peer-reviewed-article-DDDT