<b>Evaluation of enhanced aqueous solubility of praziquantel incorporated in poly (3-hydroxybutyrate) and Eudragit<sup>®</sup> E microspheres</b> - doi: 10.4025/actascihealthsci.v35i1.10673 <b>Avaliação do aumento da solubilidade aquosa do praziquantel incorporado em microesferas de poli(3-hidroxibutirato) e Eudragit<sup>®</sup> E</b> - doi: 10.4025/actascihealthsci.v35i1.10673

Praziquantel is the drug of choice for the treatment of schistosomiasis, however, its low water solubility may undermine the oral bioavailability. In this study, praziquantel was incorporated into microspheres prepared with poly(3-hydroxybutyrate) (PHB) and a polymethacrylate (Eudragit<sup>®&l...

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Bibliographic Details
Main Authors: Melissa Zétola, Elizabeth Cristina Brüske, Gabriela Tambosi, Giovana Carolina Bazzo, Bianca Ramos Pezzini
Format: Article
Language:English
Published: Universidade Estadual de Maringá 2013-03-01
Series:Acta Scientiarum. Health Sciences
Subjects:
Online Access:http://www.periodicos.uem.br/ojs/index.php/ActaSciHealthSci/article/view/10673