The structural and functional organization of the podocyte filtration slits is regulated by Tjp1/ZO-1.

Blood filtration in the kidney glomerulus is essential for physiological homeostasis. The filtration apparatus of the kidney glomerulus is composed of three distinct components: the fenestrated endothelial cells, the glomerular basement membrane, and interdigitating foot processes of podocytes that...

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Bibliographic Details
Main Authors: Masahiko Itoh, Kazuhiko Nakadate, Yasuhiro Horibata, Taiji Matsusaka, Jianliang Xu, Walter Hunziker, Hiroyuki Sugimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153657?pdf=render