How T Cells Do the “Search for the Needle in the Haystack”

In the body, a T cell is confronted with millions of antigen-presenting cells (APCs) in the search for potentially harmful antigen. To elicit an appropriate immune response, this search has to be performed as fast and as precise as possible. These two requirements, however, are at odds with each oth...

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Bibliographic Details
Main Authors: Florian Baumgart, Magdalena Schneider, Gerhard J. Schütz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphy.2019.00011/full