ATF4-mediated histone deacetylase HDAC1 promotes the progression of acute pancreatitis

Abstract Acute pancreatitis (AP), an acute inflammatory process, can be difficult to diagnose. Activating transcription factor 4 (ATF4) has been reported to participate in the pathogenesis of AP. Additionally, histone deacetylases (HDACs) are shown to be closely related to the development of a varie...

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Bibliographic Details
Main Authors: Xiaofeng Deng, Yu He, Xiongying Miao, Bo Yu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03296-x