Minimal oscillating subnetwork in the Huang-Ferrell model of the MAPK cascade.

Prompted by the recent growing evidence of oscillatory behavior involving MAPK cascades we present a systematic approach of analyzing models and elucidating the nature of biochemical oscillations based on reaction network theory. In particular, we formulate a minimal biochemically consistent mass ac...

Full description

Bibliographic Details
Main Authors: Otto Hadač, František Muzika, Vladislav Nevoral, Michal Přibyl, Igor Schreiber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5479530?pdf=render