A comparative study of endoderm differentiation in humans and chimpanzees

Abstract Background There is substantial interest in the evolutionary forces that shaped the regulatory framework in early human development. Progress in this area has been slow because it is difficult to obtain relevant biological samples. Induced pluripotent stem cells (iPSCs) may provide the abil...

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Bibliographic Details
Main Authors: Lauren E. Blake, Samantha M. Thomas, John D. Blischak, Chiaowen Joyce Hsiao, Claudia Chavarria, Marsha Myrthil, Yoav Gilad, Bryan J. Pavlovic
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-018-1490-5