Downregulation of Skp2 Expression Inhibits Malignant Phenotype of Osteosarcoma U2OS Cells
Objective To detect the effect of Skp2 knockdown on the proliferation, cell cycle, apoptosis and migration of osteosarcoma cells, and explore the molecular mechanism. Methods U2OS cells were transfected with control siRNA or human Skp2 siRNAs. The gene silence efficiency was verified by RT- qPCR and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Magazine House of Cancer Research on Prevention and Treatment
2019-05-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1339.htm |