The flavonoid isoquercitrin promotes neurite elongation by reducing RhoA activity.

BACKGROUND: Neurite formation and synaptic patterning are fundamental to the development of a functional nervous system. Flavonoids are natural molecules known for having beneficial effects on brain health through diverse molecular pathways. Cytoskeletal changes occurring during neuritogenesis and s...

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Bibliographic Details
Main Authors: Gemma Palazzolo, Peter Horvath, Marcy Zenobi-Wong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3510166?pdf=render