Human Herpesvirus 6B Greatly Increases Risk of Depression by Activating Hypothalamic-Pituitary -Adrenal Axis during Latent Phase of Infection

Human Herpesvirus 6B Greatly Increases Risk of Depression by Activating Hypothalamic-Pituitary -Adrenal Axis during Latent Phase of Infection

Summary: Little is known about the effect of latent-phase herpesviruses on their host. Human herpesvirus 6B (HHV-6B) is one of the most ubiquitous herpesviruses, and olfactory astrocytes are one of the most important sites of its latency. Here, we identified SITH-1, an HHV-6B latent protein specific...

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Bibliographic Details
Main Authors: Nobuyuki Kobayashi, Naomi Oka, Mayumi Takahashi, Kazuya Shimada, Azusa Ishii, Yoshitaka Tatebayashi, Masahiro Shigeta, Hiroyuki Yanagisawa, Kazuhiro Kondo
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Molecular Biology
Behavioral Neuroscience
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220303722

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http://www.sciencedirect.com/science/article/pii/S2589004220303722

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