Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis

Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis

Chronic inflammation contributes to tumor initiation in colitis-associated colorectal cancer (CRC). Indeed, inflammatory bowel disease (IBD) patients show an increased risk of developing CRC. Cancer immune evasion is a major issue in CRC and preclinical and clinical evidence has defined a critical r...

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Bibliographic Details
Main Authors: Paola De Cicco, Theodore Sanders, Giuseppe Cirino, Kevin J. Maloy, Angela Ianaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Immunology
Subjects:
colitis-associated cancer
colorectal cancer
cystathionine gamma-lyase
cystathionine beta-synthase
Helicobacter hepaticus
hydrogen sulfide
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00499/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00499/full

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