Phosphatidylcholine alteration identified using MALDI imaging MS in HBV-infected mouse livers and virus-mediated regeneration defects.

In this study, we investigated whether hepatitis B virus (HBV) causes the alteration of lipid metabolism and composition during acute infection and liver regeneration in a mouse model. The liver controls lipid biogenesis and bile acid homeostasis. Infection of HBV causes various liver diseases and i...

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Bibliographic Details
Main Authors: Eun-Sook Park, Jeong Hwa Lee, Ji Hye Hong, Yong Kwang Park, Joon Won Lee, Won-Jae Lee, Jae Won Lee, Kwang Pyo Kim, Kyun-Hwan Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4125171?pdf=render