Hypoxic Tumor Microenvironments Reduce Collagen I Fiber Density

Although the mechanisms through which hypoxia influences several phenotypic characteristics such as angiogenesis, selection for resistance to apoptosis, resistance to radiation and chemotherapy, and increased invasion and metastasis are well characterized, the relationship between tumor hypoxia and...

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Bibliographic Details
Main Authors: Samata M. Kakkad, Meiyappan Solaiyappan, Brian O’Rourke, Ioannis Stasinopoulos, Ellen Ackerstaff, Venu Raman, Zaver M. Bhujwalla, Kristine Glunde
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800624