Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic

<p>Abstract</p> <p>Background</p> <p>Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is...

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Bibliographic Details
Main Authors: Singh Keshav K, Kachhap Sushant
Format: Article
Language:English
Published: BMC 2004-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/3/1/32