A Mathematical Model of Immune-System-Melanoma Competition

We present a mathematical model developed to reproduce the immune response entitled with the combined administration of activated OT1 cytotoxic T lymphocytes (CTLs) and Anti-CD137 monoclonal antibodies. The treatment is directed against melanoma in B16 OVA mouse models exposed to a specific immunoth...

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Bibliographic Details
Main Author: Marzio Pennisi
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2012/850754