Adaptation and Sensitization to Proteotoxic Stress

Although severe stress can elicit toxicity, mild stress often elicits adaptations. Here we review the literature on stress-induced adaptations versus stress sensitization in models of neurodegenerative diseases. We also describe our recent findings that chronic proteotoxic stress can elicit adaptati...

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Bibliographic Details
Main Author: Rehana K. Leak
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Dose-Response
Online Access:https://doi.org/10.2203/dose-response.13-016.Leak