Impaired hypothalamic mTOR activation in the adult rat offspring born to mothers fed a low-protein diet.

Several epidemiological and experimental studies have clearly established that maternal malnutrition induces a high risk of developing obesity and related metabolic diseases in the offspring. To determine if altered nutrient sensing might underlie this enhanced disease susceptibility, here we examin...

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Bibliographic Details
Main Authors: Omar Guzmán-Quevedo, Raquel Da Silva Aragão, Georgina Pérez García, Rhowena J B Matos, André de Sa Braga Oliveira, Raul Manhães de Castro, Francisco Bolaños-Jiménez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767644?pdf=render