Hyperosmolarity Triggers the Warburg Effect in Chinese Hamster Ovary Cells and Reveals a Reduced Mitochondria Horsepower

Hyperosmolarity Triggers the Warburg Effect in Chinese Hamster Ovary Cells and Reveals a Reduced Mitochondria Horsepower

Tumor cells are known to favor a glycolytic metabolism over oxidative phosphorylation (OxPhos), which takes place in mitochondria, to produce the energy and building blocks essential for cell maintenance and cell growth. This phenotypic property of tumor cells gives them several advantages over norm...

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Bibliographic Details
Main Authors: Jorgelindo da Veiga Moreira, Lenny De Staercke, Pablo César Martínez-Basilio, Sandrine Gauthier-Thibodeau, Léa Montégut, Laurent Schwartz, Mario Jolicoeur
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Metabolites
Subjects:
CHO cells
Warburg effect
hyperosmolarity
lipoic acid
hydroxycitrate
mitochondrial hyperfusion
Online Access:https://www.mdpi.com/2218-1989/11/6/344

Internet

https://www.mdpi.com/2218-1989/11/6/344

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