Human Trial of a Genetically Modified Herpes Simplex Virus for Rapid Detection of Positive Peritoneal Cytology in the Staging of Pancreatic Cancer

Human Trial of a Genetically Modified Herpes Simplex Virus for Rapid Detection of Positive Peritoneal Cytology in the Staging of Pancreatic Cancer

Introduction: Patients with peritoneal dissemination of pancreatic adenocarcinoma do not benefit from surgical resection, but radiologic and cytologic detection of peritoneal cancer lack sensitivity. This trial sought to determine if an oncolytic virus may be used as a diagnostic agent to detect per...

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Bibliographic Details
Main Authors: Kaitlyn J. Kelly, Joyce Wong, Mithat Gönen, Peter Allen, Murray Brennan, Daniel Coit, Yuman Fong
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:EBioMedicine
Subjects:
Pancreatic adenocarcinoma
Oncolytic viral therapy
Herpes simplex virus
Peritoneal fluid cytology
Diagnostic laparoscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416301293

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http://www.sciencedirect.com/science/article/pii/S2352396416301293

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