The Critical Role of TRIB2 in Cancer and Therapy Resistance

The Tribbles pseudokinases family consists of TRIB1, TRIB2, TRIB3 and STK40 and, although evolutionarily conserved, they have distinctive characteristics. Tribbles members are expressed in a context and cell compartment-dependent manner. For example, TRIB1 and TRIB2 have potent oncogenic activities...

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Bibliographic Details
Main Authors: Victor Mayoral-Varo, Lucía Jiménez, Wolfgang Link
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/11/2701