Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells

Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells

Esophageal adenocarcinoma (EAC) is a highly lethal cancer type with an overall poor survival rate. Twenty to thirty percent of EAC overexpress the human epidermal growth factor receptor 2 (Her2), a transmembrane receptor tyrosine kinase promoting cell growth and proliferation. Patients with Her2 ove...

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Bibliographic Details
Main Authors: Félice A. Janser, Olivia Adams, Vanessa Bütler, Anna M. Schläfli, Bastian Dislich, Christian A. Seiler, Dino Kröll, Rupert Langer, Mario P. Tschan
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy
Her2
Lapatinib
LC3B
p62
OE19
Her2 inhibitor
resistance
esophageal adenocarcinoma
Online Access:http://www.mdpi.com/1422-0067/19/10/3069

Internet

http://www.mdpi.com/1422-0067/19/10/3069

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