Affinity and avidity models in autoimmune disease

Affinity and avidity models in autoimmune disease

In this work, we develop a theoretical model of affinity and avidity in the immune system.The model is based on an extension of the Cubic Ternary Complex (CTC) model of receptor - ligandinteractions to the immunological synapse setting. We use the resulting equation to study how lysiscan occur for a...

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Bibliographic Details
Main Author: James Peterson
Format: Article
Language:English
Published: American Institute of Mathematical Sciences 2018-04-01
Series:AIMS Allergy and Immunology
Subjects:
T cell models
cubic ternary complex receptor
ligand interactions
immunological kinapses and synapses
self versus non-self computations
affinity
efficacy and avidity models
Online Access:http://www.aimspress.com/Allergy/article/1925/fulltext.html

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http://www.aimspress.com/Allergy/article/1925/fulltext.html

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