NPY Receptor 2 Mediates NPY Antidepressant Effect in the mPFC of LPS Rat by Suppressing NLRP3 Signaling Pathway

Accumulated evidences show that neuroinflammation play a pivotal role in the pathogenesis of depression. Neuropeptide Y (NPY) and its receptors have been demonstrated to have anti-inflammative as well as antidepressant effects. In the present study, the ability of NPY to modulate depressive-like beh...

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Bibliographic Details
Main Authors: Wenjiao Wang, Tao Xu, Xinyue Chen, Kemeng Dong, Chunkai Du, Jing Sun, Cuige Shi, Xiaoxiao Li, Yutao Yang, Hui Li, Zhi-Qing David Xu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/7898095