Establishment of Neurospora crassa as a host for heterologous protein production using a human antibody fragment as a model product

Establishment of Neurospora crassa as a host for heterologous protein production using a human antibody fragment as a model product

Abstract Background Filamentous fungi are commonly used as production hosts for bulk enzymes in biotechnological applications. Their robust and quick growth combined with their ability to secrete large amounts of protein directly into the culture medium makes fungi appealing organisms for the genera...

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Bibliographic Details
Main Authors: David Havlik, Ulrike Brandt, Kathrin Bohle, André Fleißner
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Microbial Cell Factories
Subjects:
Neurospora crassa
Heterologous proteins
Antibody fragments
Fusion protein
Proteases
Bioreactor
Online Access:http://link.springer.com/article/10.1186/s12934-017-0734-5

Internet

http://link.springer.com/article/10.1186/s12934-017-0734-5

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