Thiopurine Drugs in the Treatment of Ulcerative Colitis: Identification of a Novel Deleterious Mutation in TPMT

Chronic inflammatory bowel disease (IBD) includes Crohn’s disease and ulcerative colitis. Both are characterized by inflammation of part of the digestive tract lining. Azathioprine (AZA) is a well-known immunosuppressant that has been known for many years for its ability to provide long-term disease...

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Bibliographic Details
Main Authors: Pierre-Olivier Harmand, Jérôme Solassol
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/10/1212