Early cytokine release in response to live Borrelia burgdorferi Sensu Lato Spirochetes is largely complement independent.

AIM: Here we investigated the role of complement activation in phagocytosis and the release of cytokines and chemokines in response to two clinical isolates: Borrelia afzelii K78, which is resistant to complement-mediated lysis, and Borrelia garinii LU59, which is complement-sensitive. METHODS: Borr...

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Bibliographic Details
Main Authors: Kerstin Sandholm, Anna J Henningsson, Susanne Säve, Sven Bergström, Pia Forsberg, Nina Jonsson, Jan Ernerudh, Kristina N Ekdahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4180076?pdf=render